MicroRNA in Human Infectious Diseases

Vijay Kumar Prajapati · Rupal Ojha

01/2024 · Elsevier

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MicroRNA in Human Infectious Diseases offers a detailed overview of the therapeutic and diagnostic role microRNAs can play in the treatment of various infectious diseases. Beginning with an introduction on microRNAs and their mechanisms, the book then delves into the therapeutic role of microRNAs in various categories of diseases: bacterial, viral, and parasitic. A wide range of diseases are explored in these sections, including sexually transmitted diseases, typhoid, tuberculosis, Dengue fever, Ebola, Covid-19, Malaria, Leishmaniasis, and Lymphatic filariasis. The final section of the book covers microRNA-based system approaches, considering aspects such as web-based tools available for detecting and predicting microRNA targets, and the latest technologies for modifying and manipulating microRNAs. This volume explores microRNA across a multitude of conditions and is an ideal reference for those involved in the investigation and development of treatments in this area. - Includes foundational knowledge on microRNAs and the fundamental aspects of its biogenesis - Explores the potential role microRNAs can play in therapeutics and diagnostics to treat various infectious diseases, including sexually-transmitted diseases, bacterial diseases, viral infections, and parasitic diseases - Features a chapter dedicated to the role of microRNA for therapeutics in respiratory viral infections, such as Covid-19 - Considers technologies used for manipulating and modifying microRNAs in preparation for applications to treat infectious diseases

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Dr. Vijay Kumar Prajapati is an Associate Professor in the Department of Biochemistry at the University of Delhi South Campus, New Delhi, India. He specializes in cell-death research, parasitology, and therapeutic developments for infectious diseases. He has published extensively in international journals and contributed chapters to reputable publishers. He is a recipient of the INSA Medal for Young Scientist from the Indian National Science Academy and an Associate of the Indian Academy of Sciences, Bengaluru. His work has appeared in leading journals spanning infectious diseases and cellular physiology, reflecting a high scholarly impact and a broad research portfolio.

Rupal Ojha’s research has highlighted the emerging role of circulating microRNA's in the diagnosing human infectious diseases. Rupal has presented her research work at the international platform on the invitation of host institutions. She has published her research work in international journals such as the International Journal of Biological Macromolecules, ACS Omega, European Journal of Pharmaceutical Sciences, and Journal of Cellular Physiology, and 3 book chapters with reputed publishers.

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